Fully integrated real time multi-wavelength photo acoustics for early disease detection


In the FULLPHASE project the partners will perform research and development on a portable multiwavelength photoacoustic medical system to be applied for point-of-care early disease detection and optimal treatment monitoring in oncology, rheumatology and CVD at the level of secondary and primary care. The integrated set of research and development activities will be divided in eight complementary work packages / work areas each with highly interdisciplinary research and developments as shown below.

In addition FULLPHASE young researchers are trained in the various technologies that are integrated in our PA/US (photoacoustics/ultrasound) scanner. FULLPHASE technology is developed in accordance to the medical needs and will lead in a commercial product ready for clinical practice.

The Objectives

The objective of FULLPHASE is the transition of PA (photoacoustics) imaging from a lab-based technique to a low-cost portable multi wavelength combined PA and US (ultrasound) system. In order to reach that goal, the FULLPHASE partners offer specific expertise over complementary backgrounds in diode laser technology, laser beam shaping, ultrasound imaging technology, and system integration. The impact of the FULLPHASE system will be shown in oncology, rheumatology and cardio vascular disease.

FULLPHASE will integrate different scientific and technological expertise, for point-of-care early diagnosis, by means of specific knowledge, which will be directed towards:

  • Multi wavelength laser diode beam source delivering very high energy pulses.
  • Highly efficient diode laser driver.
  • Multi-wavelength diffractive optical beam shaping.
  • Optimal light delivery.
  • PA imaging depth of a few centimeters.
  • Advanced beam forming and temporal resolution.
  • Quantitative functional and structural imaging.
  • In-vitro and ex-vivo verification.
  • Preclinical validation.

For more information: http://www.fullphase-fp7.eu/


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